Similar familial risk in multiple sclerosis subgroups
نویسندگان
چکیده
منابع مشابه
Familial risk of multiple sclerosis: a nationwide cohort study.
Multiple sclerosis (MS) is known to accumulate within families. The magnitude of the familial risk, however, remains uncertain. Using a nationwide MS register and other national registers, the authors estimated relative and absolute risks of MS in a population-based cohort that included 19,615 first-degree relatives of 8,205 Danish MS patients followed from 1968 to 1997. The ratio of observed t...
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Background Multiple sclerosis (MS) is one of the chronic autoimmune diseases and a progressive disease of the central nervous system that have unknown causes. Objective This study aims to review the environmental risk factors of MS. Methods In this review study, a search was conducted in databases such as PubMed, Scopus, ScienceDirect, Google Scholar and MagIran on related studies published i...
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Multiple sclerosis (MS) is an inflammatory disease characterized by myelin loss and neuronal dysfunction. Despite the aggregation observed in some families, pathogenic mutations have remained elusive. In this study, we describe the identification of NR1H3 p.Arg415Gln in seven MS patients from two multi-incident families presenting severe and progressive disease, with an average age at onset of ...
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multiple sclerosis (ms) is an autoimmune disease of central nervous system. since different types of immune cells are involved in ms pathogenesis, in this study we aimed to evaluate serum levels of several immunological components including soluble cd4 (scd4), scd8, scd163, and immunoglobulins as markers of activity of t-cells, macrophages, and b-cells in different types of ms. serum levels of ...
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We report here two cases of cavernous angioma, in the proband and her father, with quite different clinical presentations. The proband presented with a brainstem syndrome, mimicking multiple sclerosis, while the father had a history of mild epilepsy. Both patients were managed conservatively. The cases also demonstrate the utility of magnetic resonance imaging in the diagnosis of cavernous angi...
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ژورنال
عنوان ژورنال: Multiple Sclerosis Journal
سال: 2017
ISSN: 1352-4585,1477-0970
DOI: 10.1177/1352458516684214